Sylvia Stickles runs a convenience store with her husband and mother-in-law. One day, Sylvia is hit on the head and transforms from an uptight prude to a sex-crazed lunatic. As she goes on a rampage through town, Sylvia attracts the attention of Ray Ray, a sexual healer and tow truck driver in search of the world's greatest orgasm. Their sexual revolution, however, causes a class war in their tiny Baltimore community.

Doug is a Secret Service Agent who has just completed his stint in charge protecting Tess Carlisle—the widow of a former U.S. President, and a close personal friend of the current President. He finds that she has requested that he not be rotated but instead return to be her permanent detail. Doug is crushed, and—after returning—wants off her detail as she is very difficult to guard and makes her detail crazy with her whims and demands.