Zeebo Newton is a small-town misfit who gets bullied, fired from his job, rejected by his dream girl, watches his best friend die, and is threatened with eviction when he is abducted and must fight for his life and everything he loves.

Three 6 Mafia's followup to the highly successful street movie Choices 1. After a heist goes wrong for two Memphis hustlers (DJ Paul and Juicy), they find themselves behind bars. Two crooked DEA agents offer freedom on the condition that they do a job for them. Juicy and Paul are forced to make a choice: stay locked up or get caught up. Set against the gritty backdrop of Memphis this film takes Juicy and Paul from the gutter to ballin' and back again.