A Woman named Rose is a virgin in her early twenties, who has a rare condition which cause her to kill every time she is sexually aroused. She tries to hide the bodies, fix herself and find out about her condition. That keeps her alone and in love with her knives. She takes up a job as a hired killer and stays single but meets another woman, named Sam, who has the same condition and has answers for her question, but does love prevail and what secrets are revealed?

"The Last Road to Hell" tells the story of three groups of criminals whose paths bring them together for a weekend they will never forget. Three kidnappers (Russ, Meiko and Kat) kidnap a woman (Patricia) and take her to a warehouse run by a demon conjuring low life (Bill). They are joined there by two young male torture fanatics (Bruce and Ray) and another group of kidnappers (Paul and company). When the two kidnapped females turn out to be more than they bargained for, all roads will lead to Hell.