Alex Whitaker and three other gifted psychics investigate rumors that the secret of life has been discovered by master puppeteer, Andre Toulon, in the form of five killer puppets uniquely qualified for murder and mayhem.

James Lake (Raymond St. Jacques) is an escaped black convict imprisoned for a murder he didn't commit. Leslie Whitlock (Kevin McCarthy) offers James money to kill his wife, Ellen (Dana Wynter). He declines and tries to look up his old flame Lily (Barbara McNair), but discovers his own brother is now married to the sultry nightclub singer. James returns to Leslie, and the trio travel towards a mountain retreat. James and Ellen escape and try to find the murderer who had framed James years before.