A romantic getaway for two troubled college sweethearts turns into a struggle for survival when unexpected guests – and the surrounding environment – exhibit signs of a mysterious infection.

It was a warm summer and Emma Tate was taking some of her friends over to Haddonfield to see her great grandmother Pamela Strode, but they soon found themselves in Emma's great uncle Michael Myers' path of destruction, as Michael came back to put the Myers and Strode family names to rest - finally ending the bloodline after many years of furiously trying and failing.