Handsome Stranger has agreed to escort Charming Jones to collect her inheritance from her father. But Avery Simpson wants the money and hires notorious outlaw Cactus Jack to ambush Charming. However, Cactus Jack is not very good at robbing people.

Rabbi Avram arrives in Philadelphia from Poland en route to San Francisco where he will be a congregation's new rabbi. An innocent and inexperienced traveller, he is tricked by con men to pay for the trip to go west, then they leave him and his belongings scattered along a deserted road. He is befriended by a stranger, Tommy, who is a bank robber and have many adventures during their journey.