Hiram is a security guard at a mansion who must help his old private investigator friend Wilson track down the missing Angelin who may be the prey of the Mississippi Mummy.

Fugitive security guard Stanley Tweedle, love slave Zev Bellringer, and love slave robot head 790 are thrown together by fate and on the run from His Divine Shadow after stealing The Lexx: the most powerful destructive force in two universes.