The film is based on the true story of the 516 Sichuan drug production and trafficking case supervised by the Ministry of Public Security. On a national highway in Dachuan City, Cao Renfan, the squadron leader of the anti-narcotics brigade, led the team and was fighting fiercely with the desperate drug traffickers who had hijacked the bus.

The genius sniper Anna is forced to accept an assassination assignment. In the process, she gradually finds her true calling to fight for kindness and to defend a greater love. Tai, a special agent for the UN army, stands up for justice when drug lords try to harm innocent citizens. The two join forces to block the bill to legalize drug cultivation and distribution in Libiwala. They fight to the death with the drug lord Luo Jie and eventually foil his plans, protecting the people from the drugs. This is the exciting story of them working together to save a nation.