One day, Annabì decides it’s enough. Her whole life has been affected by her fear of flying and so has her career. She is a successful actress but has turned down many roles abroad because flying is an insurmountable obstacle for her. Now, her daughter Serena has decided to study in California. Obsessed with the idea of not being a good mother, Annabì forces herself to cross the dreaded threshold of Fiumicino airport and to head to a secluded area where a course will take place. Other mysterious travelers are heading to the same place, all of them with their own baggage of fears and willing to overcome their aerophobia.

Carlo Verdone plays himself by portraying the drama and the comedy of his private life and his relationship with a loving and oppressive mother: Rome.