An orphaned and accomplished cardiologist, Dr. Khanyaqhawe Mabuyakhulu is challenged when she has found out she has to operate on Bheki, a man that killed her mother.

High Rollers is a South African television drama series-turned-telenovela created by Joshua Rous and Luke Rous and produced by Rous House Productions which is an inter-generational family drama set against the backdrop of the glamorous and backstabbing world of gambling.