As Stitch, a runaway genetic experiment from a faraway planet, wreaks havoc on the Hawaiian Islands, he becomes the mischievous adopted alien "puppy" of an independent little girl named Lilo and learns about loyalty, friendship, and ʻohana, the Hawaiian tradition of family.

Babe, fresh from his victory in the sheepherding contest, returns to Farmer Hoggett's farm, but after Farmer Hoggett is injured and unable to work, Babe has to go to the big city to save the farm.