A lost dog, a cassette tape, and a backyard comedy show bring two Asian-American strangers together for a day they'll never forget.

A crack-pot scientist aligns with the Axis of Evil to bring down the United States with EMP blasts, toxic zombification gas and by unleashing the ultimate undead killing monstrosity: the Z-REX. When a hot-wired militia squad and a crew of college hipsters are thrown together to do something about it, chaotic Predator-Thunder action runs amok.

Alex is a lonely accountant whose one act of rage results in her being sentenced to court-ordered therapy. There she meets Stella, the owner of a small extermination business who uses her car as a weapon, and Nikki, a dental technician with the face of an angel and the mind of a sociopath. Together these women form their own "silent revolution", wreaking havoc on the abusive men in their lives.