Rome, 1990. The night Italy's national football team is eliminated from the World Cup by Argentina on penalty kicks, a well-known film producer is found dead in the Tiber river. The main suspects for the murder are three young aspiring screenwriters, who–promptly taken to the police–start to tell their version of the story.

An old bus drives through the streets of Rome. It's a long day. The bus fills up with people and stories. Then empties out. People get on. And get off. Faces, eyes. Expectations. A few encounters. Incidents. Slips. Ambiguities. Thefts. Rows. Confiding exchanges. Confessions. Projects. Plans. Lies. Slaps. Even one hijacking. A well-defined route can become a journey. Each encounter can become a future opportunity or can lay a former wound to rest. Every stop may produce the person who will change your life trajectory. Or not, and the bus carries on. At the next turn, someone else will get on and a fragment of his life will for a moment touch yours.

Marcelline is an actress. Forty, single and childless, she begins rehearsals for Turgenev’s A Month in the Country. Denis, the director, admires her greatly and promises he’ll make her happy on stage — she will shine. But things don’t go to plan.

Ugo and Francesca have been married for ten years, but mutually decide to break up in a graceful way. They start singles' life again, having to deal with their children, their jobs and social relationships alone. They even both start seeing someone else, until jealousy arises. Perhaps their love is not over yet...

It’s a hard life for young Leo: his family just doesn’t understand why he’s a vegetarian lion. His solitude ends when he meets Avoria, the elephant queen, who has recently given birth to two calves with braided tails. Mysteriously widowed, Avoria is courted by dapper Zanco. By a series of misfortunes she is separated from her young. Leo steps in to take care of them: thus begins his search for legendary Milk Lake, during which he experiences all sorts of incredible adventures. This fable with a happy ending handles the themes of diversity and racism with engaging originality.

Luca is a famous actor working on his new film as both its star and director. One day he gets extremely sick and, while at the hospital, rethinks his life.

Don Matteo is a thoroughly ordinary Catholic priest with an extraordinary ability to read people and solve crimes. He’s a parish priest who never met an unjustly accused person he didn’t want to help.

Working together with his friend Leo as a waiter in a dining car, Simone discovers that Silvia, a girl with whom he had a casual relationship, is pregnant and wants to keep the baby.

Sergio has a degree in botanics, but cannot find a job. Then, he gets the announcement that his former girlfriend is getting married.

The housing shortage means that two spouses have to continue living under the same roof despite the ongoing legal separation. Incidents and misunderstandings to no end, but the couple's son will take care of fixing everything.

Leon de Paris is a modest dog-barber in Paris. In search of more satisfaction. Thanks to the economic helps of Fanny (his terrible mother in law), he succeeds to set up in Roma a very stylish "Coiffeur pour homme". But due to this, his life with Fanny isn't funny, and more, Leon has to dissimulate homosexuality for job reasons. He decides to stop this nightmare engaging "Er Cuculo" (the cuckoo) a B-gangster to simulate a robbery. In fact the plan is to take all Fanny's money, share it among them and escape in Montecarlo. Will the strange couple succeed?