A widowed trucker fends off isolation in the company of a dog named Girl, two bickering sisters try to reconcile their differences and a down-and-out circus clown and his stripper girlfriend must fight the temptation of crime on the road. Their common companion is an angry disc jockey at odds with a desperate boss. All these people will find their lives intertwined by the hand of fate. And before the night gives way to day, some will breathe their last breath... Outside Ozona.

Two losers from Milwaukee, Coop and Remer, invent a new game playing basketball, using baseball rules. When the game becomes a huge success, they, along with a billionaire's help, form the Professional Baseketball League where everyone gets the same pay and no team can change cities. Theirs is the only team standing in the way of major rule changes that the owner of a rival team wants to institute.