Sheena's parents were archaeologists who died in the jungle when she was about six years old, leaving their daughter Shirley Hamilton. She was taken in by Kali, a local Shamaness of a tribe who brought her up, and five years ago she was taught how to morph into animals and birds, acquiring their abilities, even flight. Further, she became a mythical creature called "The Darachna" who relies on people' fear of the unknown. For this she covers herself in a dark liquid mud which allows her to be largely unseen in the low light of the jungle, and with more than normal strength, agility and speed, and armed with a pair of gloves with bone claws, she is a formidable one woman fighting force. She does kill sometimes.

In the sleepy town of Vine Creek, preacher and volunteer fireman Joe Cass wakes up to realize his family and community are at a breaking point. Joe decides to take control of his life and must prove his bravery when he is called to save a child trapped inside a burning building. Lost inside the inferno, a mysterious fireman helps them to safety and quickly disappears. As Joe waits for the mystery fireman to come forward, rumors circulate throughout Vine Creek that the apparition was an angel sent from above.

Following the suicide of her only friend, outcast teen Rachel Lang's life begins a downward spiral that will not only affect her but take everyone around her down in horrifying fashion.