In 35,000 BC, the tribe of the Dirty Hairs is at war against the tribe of the Clean Hairs for eight hundred years, trying to get their shampoo. The chief of the Dirty Hairs sends his daughter Guy disguised to the enemy tribe to get some shampoo for his tribe. When the healer of the Clean Hairs tribe surprisingly kills two cavemen of his tribe, their imbecile chief assigns Pierre with curled hair and Pierre blonde to investigate the murder and find the criminal.

After hiding his loot and getting thrown in jail, Ruby, a brooding outlaw encounters Quentin, a dim-witted and garrulous giant who befriends him. After Quentin botches a solo escape attempt, they make a break together. Unable to shake the clumsy Quentin Ruby is forced to take him along as he pursues his former partners in crime to avenge the death of the woman he loved and get to the money.

A chubby forty-ish florist is dumped for a gorgeous young woman. She decides to lose weight and to ruin her rival's life in order to win her handsome lover back.

Sydney Fox is a professor and globe-trotting "relic hunter" who looks for ancient artifacts to return to museums and/or the descendants of the original owner. She is aided by her linguistic assistant Nigel and occasionally by her somewhat air-headed secretary Claudia. She often ends up battling rival hunters seeking out artifacts for the money.

The renowned Insurance International Co. has created an enquiry network, headed by detective Jack Clementi, to defend itself against insurance fraud. Jack has saved the company enormous amounts of money throughout his successful investigations and his bosses are more than willing put up with his brusque manners, his disconcerting frankness, and his intolerance for any form of company bureaucracy. Yet he is a big guy with a huge heart.