October 2015. French customs seize seven tonnes of cannabis in the heart of the capital. The same day, Hubert Antoine, a former mole with a shady past, contacts Stéphane Vilner, a journalist at Libération. He claims to be able to demonstrate the existence of State drug trafficking led by Jacques Billard, prominent media figure and high-ranking French police officer. Suspicious at first, the young journalist finally dives into an investigation that will lead him to the darkest corners of the Republic.

Mikael is doctor on night call. It’s a vocation. Between two patient-visits in slum areas, he cares for those whom no one else wants to see: the drug addicts, the homeless… He rubs shoulders with destitution. His life is in shambles. Especially when it comes to his pharmacist cousin who makes him write false prescriptions for Subutex. Overnight, he decides to get out of drug trafficking and rebuild his life. But there will be a heavy price to pay.

During the 1970s a student named Gilles gets entangled in contemporary political turmoils although he would rather just be a creative artist. While torn between his solidarity to his friends and his personal ambitions he falls in love with Christine.

Thomas has been estranged from his brother Luc for several years, due in part to his difficulties in dealing with Luc's homosexuality. But when Thomas is diagnosed with a rare blood disease, which is difficult to treat and impossible to cure, he decides he wants to bring Luc back into his life. The brothers soon become inseparable, and their new relationship begins to alienate their significant others.

Delphine meets Manuel. Fragile and elusive, the young man escapes him. Manuel leaves the city to flee his illness, a cancer. Delphine goes in pursuit and plunges into a world of dark encounters.

Friends of a recently painter Jean-Baptiste Emmerich gather at a Paris railroad station for a four-hour journey to Limoges, where Emmerich wanted to be buried. The dozen travelers include art historian François and his lover Louis, who develops an interest in Bruno, whom he meets on a train. Traveling parallel with the train is a station wagon with Jean-Baptiste's body, and this vehicle is driven by Thierry, husband of Catherine, who's on the train with their daughter. François plays a taped interview with Jean-Baptiste, revealing his sexual appeal to both men and women. Lucie is convinced that she was his main love. Also on board is his nephew, Jean-Marie and Jean-Marie's estranged wife Claire. After the funeral in "Europe's largest cemetery," the story continues in the mansion of Jean-Baptiste's brother Lucien.