Intrepid tax investigator Ryoko Itakura sets her sights on the mysterious and philandering Hideki Gondo, a suspected millionaire and proprietor of a thriving chain of seedy hourly hotels, who has for years succeeded at hiding the true extent of his assets from the Japanese authorities. Itakura and Gondo soon find themselves engaged in a complicated, satirical battle of wits.

In this humorous paean to the joys of food, a pair of truck drivers happen onto a decrepit roadside shop selling ramen noodles. The widowed owner, Tampopo, begs them to help her turn her establishment into a paragon of the "art of noodle-soup making". Interspersed are satirical vignettes about the importance of food to different aspects of human life.