When a sudden plague of blindness devastates a city, a small group of the afflicted band together to triumphantly overcome the horrific conditions of their imposed quarantine.

Degrassi High is the third television show in the Degrassi series of teen dramas about the lives of a group of teenagers living on or near De Grassi Street in Toronto, Ontario, Canada. It first aired from 1989 to 1991 and followed the young people from The Kids of Degrassi Street and Degrassi Junior High through high school. The show was filmed in downtown Toronto and at Centennial College. Much like its predecessor, Degrassi High dealt with controversial issues ranging from AIDS, abortion, abuse, alcoholism, cheating, sex, death and suicide, dating, depression, bullying, gay rights, homophobia, racism, the environment, drugs, and eating disorders. The show's impact on Canadian identity is discussed in the September 2007 issue of u're Magazine.

Degrassi Junior High is a Canadian CBC Television teen drama series that was produced from 1987-1989 as part of the Degrassi series. The show followed the lives of a group of students attending the titular fictional school. Many episodes tackled difficult topics such as drug use, child abuse, teenage pregnancy, homosexuality, homophobia, racism, and divorce, and the series was acclaimed for its sensitive and realistic portrayal of the challenges of teenage life. The cast comprised mainly non-professional actors, which added to the show's sense of realism. The series featured many of the same actors who had starred on The Kids of Degrassi Street a few years earlier, including Stacie Mistysyn, Neil Hope, Anais Granofsky, Sarah Charlesworth and others. However, their character names and family situations had been changed, so Degrassi Junior High cannot, therefore, be considered a direct spinoff. The legal counsel for all the episodes was Stephen Stohn who later became the executive producer of Degrassi: The Next Generation. The series was filmed at the unused Vincent Massey Public School in Etobicoke, Ontario.

The Kids of Degrassi Street is a Canadian children's TV show that aired from 1979 to 1986, and is the first in the Degrassi series, about the lives of a group of children living on Degrassi Street in Toronto, Canada. It grew out of four short films: Ida Makes a Movie, Cookie Goes to the Hospital, Irene Moves In and Noel Buys a Suit, which originally aired as after-school specials on CBC Television in 1979, 1980, 1981 and 1982, respectively. The show was acclaimed for its realistic depiction of every day children's lives and tribulations, and remains memorable to many Canadians because of this. Kids of Degrassi Street featured many of the same actors who would later appear on Degrassi Junior High and Degrassi High, including Stacie Mistysyn, Neil Hope, Anais Granofsky, Sarah Charlesworth and others. However, their character names and families were different, so this series cannot technically be seen as an immediate precursor to the later shows.