Just how far would you go to get financing for your business? Donald Chandler is the owner of a restaurant who suddenly finds himself without a business or a job when his wife leaves him, taking the deed to the eatery with her. Eager to start over, Donald goes into a business partnership with Miguel Sanchez, a gardener who was taking care of Donald's lawn until he won a fortune in the lottery.

ER explores the inner workings of an urban teaching hospital and the critical issues faced by the dedicated physicians and staff of its overburdened emergency room.