In Miami, Florida, biker gang leader Edward "Diablo" Santer is about to be executed for murder when he proclaims his innocence and vows revenge from the grave. When a mysterious biker comes to town during Spring Break festivities, leaving several teenagers electrocuted to death, some begin to suspect that Santer has made good on his promise.

A scientist at a Florida university inadvertently creates a "rage virus" while performing experiments intended to restore dead brain tissue in baboons. When a journalist for the college paper breaks into the campus lab, he's bitten by one of the infected baboons; the virus soon spreads to a trio of rapists and a valley girl, all of whom go on killing sprees.

Kate's a single mom rock star recovering from a nervous breakdown; David is her psychiatrist turned lover. After David buys an old Charleston mansion and Kate and her son move in with him, strange events occur including the discoveries of a secret hidden attic and the diary of the murderous slave trader who owned the home. Kate hears a piano playing by itself and sees the ghost of the slave trader who once lived there. Their relationship is strained by the bizarre events as Kate's sanity is again questioned as she insists what she's seen is real...but is it?

A priest helps the small town he's stationed in to resolve conflicts by working together.