Although awkward college student Todd Howard is particularly adept at science, he's paying for school with an athletic scholarship that he will lose should he not fare well in an upcoming boxing tournament. Luckily for Todd, he has inherited the same family curse that once turned his cousin into a werewolf. As he transforms into the hairy, fanged, howling monster, he finds both his physical agility and his popularity skyrocketing -- but at what cost?

Molly, Val and Gina are graduating college, but on their final night, frustrations are aired. Molly is still looking for real love and Val is beginning to doubt if that is what she has found. Gina is too busy videotaping everything to really notice. When the final party at Pacifica College kicks off, things do not go exactly as planned.

The pupils at a high school next to a nuclear power plant start acting and looking strange after buying contaminated drugs from a plant worker.