PCP is unexplainably released into the Frankfurt water supply and sends the zoo inhabitants crazy. One evening after a malfunction of zoo security the gonzo critters rampage through the city eating and killing whatever they fancy, wreaking a night of bloody terror. It's up to regular Italian-trash whipping girl Lorraine De Selle and obnoxious Super Mario lookalike zookeeper John Aldrich to sort it out.

Since her husband is distracted by his passion for horse racing, Lucia decides to make him jealous by pretending to be the lover of his bodyguard, Diego.

David and his wife Gilda transform their beautiful villa in a brothel, which are home to several characters. Odile, the daughter of a woman tortured by mercenaries, meets in the villa one of the torturers and want to relive over his own body the suffering endured by the mother. An ambassador who was abandoned by his companion, imposes its new partner to take his place. An eighteen year old, very open-minded, staged an orgy.

A high school student falls in love with the provocative substitute, but she prefers the gym teacher.