Polizeiruf 110 is a long-running German language detective television series. The first episode was broadcast 27 June 1971 in the German Democratic Republic, and after the dissolution of Fernsehen der DDR the series was picked up by ARD. It was originally created as a counterpart to the West German series Tatort, and quickly became a public favorite.

Germany in 1943. The Berlin worker Klaus Hartung is deployed as a soldier to the Eastern front during World War II. During a tour, he is captured by a Russian patrol. While in captivity, Hartung comes to the conclusion that he has to come through and actively take part in the effort to end the war. He consents to abduct a German officer together with two Russian soldiers. During their adventurous mission, the men who at first had been enemies, become sincere friends.

In the 21st century, a global socialist security organization is concerned over a new energy source, of possible alien origin, falling into the hands of one of the last remaining capitalist countries and turned into a super-weapon.

Professor Hans Mamlock is the distinguished chief of surgery in a university hospital. The year is 1933, and although the Professor is Jewish, he remains unconcerned with politics and the growing Nazi threat. Mamlock identifies strongly as a German, and he believes his culture to be simply incapable of the common barbarism associated with the Nazi party. Accordingly, he shows little understanding for people with strong or unpopular political views, such as Walter, a patient, and Rolf, his own son. Indeed, when Rolf joins the communists in resisting the Nazis, Mamlock throws him out of his house. As the persecution of Jews intensifies during the 1930s, Mamlock's own daughter is targeted for anti-Semitic attacks at her school...