For an initiation stunt, five college women are locked in a Kentucky hospital built in 1910 where 63,000 people died from a disease known as the "white plague". Deep under the hospital is the "Death Tunnel" which once were used to secretly remove the dead from the grounds.

The film watches as horrific events inspire two young women to set out on a cross-country trail of chaos in their mobile tattoo van. With deviant subjects lurking around every corner, they devise an experiment that’s part human trials and full vigilante justice. Their avant garde methods go viral and ignite a social movement.