In the late 21st century, a subculture of humans have emerged who have been modified genetically by a vampire-like disease, giving them enhanced speed, incredible stamina and acute intelligence. As they are set apart from "normal" and "healthy" humans, the world is pushed to the brink of worldwide civil war aimed at the destruction of the "diseased" population. In the middle of this crossed-fire is - an infected woman - Ultraviolet, who finds herself protecting a nine-year-old boy who has been marked for death by the human government as he is believed to be a threat to humans.

A Hong Kong detective suffers a fatal accident involving a mysterious medallion and is transformed into an immortal warrior with superhuman powers.

An evil Duke attempts to kill and collect the blood of a royal family of European vampires in order to become all powerful. The only surviving member of the family travels to Hong Kong, only to complicate his struggle by falling in love with a mortal girl who just happens to have a vampire hunter for a brother.

A mysterious woman, known as Madame M, kidnaps forty pre-teen girls and transports them to a remote island to train them as the most deadly assassins. CIA operative Jack Chen follows the case for 6 years with no leads, but when a series of assassinations begin to occur, Jack suspects that Madame M is back in business.