An intuitive young neurosurgeon discovers that she is the unlikely heir to a family of witches. As she grapples with her newfound powers, she must contend with a sinister presence that has haunted her family for generations.

After the brutal death of a friend, a group of friends find themselves in possession of a video-game called "Stay Alive," a blood-curdling true story of a 17th century noblewoman known as the Blood Countess. After playing the game when they know they shouldn't, however, the friends realize that once they die in the game — they die for real!