Dealing with a sociopathic school bully, three high school freshmen hire a low-budget bodyguard to protect them, not realizing he is just a homeless beggar and petty thief looking for some easy cash.

Relationship issues arise between a researcher with a theory to explain away all his failed dating experiments, a player who wants out of the game, a deejay whose head spins with thoughts of God, a hoodrat with no street cred, a poet not-so-well-versed in the art of love, and a womanipulator of men.

Ben and Katie Jordan are a married couple who go through hard times in fifteen years of marriage.

Reverend Eric Camden and his wife Annie have always had their hands full caring for seven children, not to mention the friends, sweethearts and spouses that continually come and go in the Camden household.

Just when George Banks has recovered from his daughter's wedding, he receives the news that she's pregnant ... and that George's wife is expecting too. He was planning on selling their home, but that's a plan that—like George—will have to change with the arrival of both a grandchild and a kid of his own.

ER explores the inner workings of an urban teaching hospital and the critical issues faced by the dedicated physicians and staff of its overburdened emergency room.