The PFL 2 mixed martial arts event for the 2018 season of the Professional Fighters League was held on June 21, 2018, at the Chicago Theatre in Chicago, Illinois. It was the second regular season event of 2018 and included only fights in the lightweight and light heavyweight divisions.

The Ultimate Fighter: Team Joanna vs. Team Cláudia Finale (also known as The Ultimate Fighter 23 Finale) was a mixed martial arts event held on July 8, 2016 at the MGM Grand Garden Arena in Las Vegas, Nevada. This event was a part of UFC International Fight Week. The event was headlined by a UFC Women's Strawweight Championship bout between current champion Joanna Jędrzejczyk and top contender Cláudia Gadelha. The pair previously met at UFC on Fox: dos Santos vs. Miocic in December 2014, with Jędrzejczyk winning via split decision.

UFC Fight Night 77: Belfort vs. Henderson 3 was a mixed martial arts event held on November 7, 2015, at the Ginásio do Ibirapuera in São Paulo, Brazil. The event was headlined by a middleweight trilogy bout between longtime multi-divisional contenders and champions Vitor Belfort and Dan Henderson. Henderson defeated Belfort in their first encounter in 2006 at Pride 32 via unanimous decision. Belfort defeated Henderson in their second encounter in 2013 at UFC Fight Night: Belfort vs. Henderson 2 via first round knockout.

UFC Fight Night 68: Boetsch vs. Henderson was a mixed martial arts event held on June 6, 2015, at the Smoothie King Center in New Orleans, Louisiana. A middleweight bout between Tim Boetsch and mixed martial arts legend Dan Henderson was the main event.

UFC Fight Night 47: Bader vs. St. Preux was a mixed martial arts event held on August 16, 2014, at the Cross Insurance Center in Bangor, Maine. The event was headlined by top ten light heavyweights Ryan Bader and Ovince Saint Preux.

UFC Fight Night 32: Belfort vs. Henderson 2 was a mixed martial arts event held on November 9, 2013, at the Goiânia Arena in Goiânia, Brazil. The event was headlined by a rematch between longtime multi-divisional contenders Vitor Belfort and Dan Henderson. Henderson defeated Belfort in their first encounter in 2006 at Pride 32 in a unanimous decision.

UFC on FX 7: Belfort vs. Bisping was a mixed martial arts event held by the Ultimate Fighting Championship on January 19, 2013, at Ginásio do Ibirapuera in São Paulo, Brazil. The main fight featured middleweights Michael Bisping and Vitor Belfort.

UFC 142: Aldo vs. Mendes was a mixed martial arts event held by the Ultimate Fighting Championship on January 14, 2012 at the HSBC Arena in Rio de Janeiro, Brazil.

UFC 134: Silva vs. Okami was a mixed martial arts event held by the Ultimate Fighting Championship on August 27, 2011 at the HSBC Arena in Rio de Janeiro, Brazil.

UFC on Versus 3: Sanchez vs. Kampmann was a mixed martial arts event held by the Ultimate Fighting Championship that took place on March 3, 2011, at the KFC Yum! Center in Louisville, Kentucky.

UFC 119: Mir vs. Cro Cop was a mixed martial arts event held by the Ultimate Fighting Championship on September 25, 2010 at Conseco Fieldhouse in Indianapolis, Indiana, United States. The event was the first that the UFC has hosted in Indiana.

UFC Fight Night 20: Maynard vs. Diaz was a mixed martial arts event held by the Ultimate Fighting Championship (UFC) on January 11, 2010 at the Patriot Center in Fairfax, Virginia.

UFC 94: St-Pierre vs. Penn 2 was a mixed martial arts event held by the Ultimate Fighting Championship (UFC) on January 31, 2009. The main event featured the rematch of the UFC Welterweight Champion Georges St-Pierre against the UFC Lightweight Champion BJ Penn for the UFC Welterweight Championship.

UFC 88: Breakthrough was a mixed martial arts event held by the Ultimate Fighting Championship (UFC) on September 6, 2008 at the Philips Arena in Atlanta, Georgia. The event was headlined by a light heavyweight bout between Chuck Liddell and Rashad Evans.

UFC 85: Bedlam was a mixed martial arts event held by the Ultimate Fighting Championship (UFC) on June 7, 2008, at The O2 Arena in London, United Kingdom. The main event was ultimately changed to Matt Hughes against Thiago Alves. Hughes took the fight on short notice as a favor to the UFC and Alves came in four pounds overweight.

UFC Fight Night 12: Swick vs. Burkman was a mixed martial arts event held by the Ultimate Fighting Championship on January 23, 2008, at the Palms Casino Resort in Las Vegas, Nevada. The main event featured former The Ultimate Fighter contestants Mike Swick and Josh Burkman in a welterweight matchup. This event was Swick's debut at welterweight, as he had been competing at middleweight prior to the show.

UFC 76: Knockout was a mixed martial arts (MMA) event held by the Ultimate Fighting Championship (UFC). The event took place on September 22, 2007 at the Honda Center in Anaheim, California. Though the event was subtitled Knockout, the entire card ironically produced no knockouts. The main event featured a fight between former Light Heavyweight Champion Chuck Liddell and The Ultimate Fighter 2 alum Keith Jardine, with both fighters returning from knockout losses at UFC 71.

UFC Fight Night 10: Stout vs. Fisher was a mixed martial arts event held by the Ultimate Fighting Championship on Tuesday, June 12, 2007, at the Seminole Hard Rock Hotel and Casino in Hollywood, Florida. The main event was a rematch from a UFC 58 fight in which Fisher was a late replacement for Stouts opponent, and he had to cut a lot of water weight just to fight. Stout won their first fight by split decision.

UFC Fight Night 9: Stevenson vs. Guillard was an event held on April 5, 2007, at The Palms Casino Resort in Las Vegas, Nevada. The main event was Joe Stevenson vs. Melvin Guillard in the lightweight division.