After resolving a situation of exorcism, the half-breed demon hunter Jake Greyman (Sean Patrick Flanery) reports to Cardinal White (William Bassett) and they realize that the demon Asmodeus (Billy Drago) is impregnating many mortals trying to raise offspring. Cardinal White calls Sister Sarah Ryan (Colleen Porch) to assist Jake in his hunting for Asmodeus and his women.

Harry Sanborn is an aged music industry exec with a fondness for younger women like Marin, his latest trophy girlfriend. Things get a little awkward when Harry suffers a heart attack at the home of Marin's mother, Erica. Left in the care of Erica and his doctor, a love triangle starts to take shape.

Molly Gunn, the freewheeling daughter of a deceased rock legend, is forced to get a job when her manager steals her money. As nanny for precocious Ray, the oft ignored daughter of a music executive she learns what it means to be an adult while teaching Ray how to be a child.

Three hit people - two men, one woman, who have never met before are placed on a road trip down the East Coast together. The only thing they have in common is that they have all worked for the same boss - and, as they swap stories, discover that they have all screwed up for this same boss in the past. As they share their stories of errors on the job - seen through visual, stirring flashbacks - they begin to wonder why it was they were put together in the first place and what might be waiting for them at the end of their little road trip.