A group of women wake up in a cold cement basement. Drugged and terrified they find themselves captive to a depraved psychopath whose blood-lust and insanity knows no bounds. Police Detective Balasco and psychiatrist Dr. Metcalfe team up in a desperate attempt to locate the girls and their soon to be murderer - a serial killer known as Ghost (Daniel Baldwin). But time is running out as Ghost's sick experiments begin to leave the girls tortured beyond recognition. To survive, the girls must band together in a last attempt to save themselves from a fate far worse than death.

Young, innocent, and quirky June (Felicia Day), a violinist, spends her days working in an oddball Venice coffee shop, her nights rehearsing for a professional music career, and all-hours daydreaming about the beautiful man that's destined just for her. When she actually meets him in her own apartment building, she finds out Jack (Chris Henry Coffey) is engaged to the quintessential gorgeous bitch, Quinn (Cindy Dolenc). The conflict ensues and the romance is tested. Whether it's indulging her loony Grandma (Ellen Geer) through rehearsals of her own funeral, or dealing with the overzealous video-store manager (Ted Michaels) and his crush, June stumbles through her potential love life, her best friend Mary at her side.