After a tragic ending to her short-lived super hero stint, Jessica Jones is rebuilding her personal life and career as a detective who gets pulled into cases involving people with extraordinary abilities in New York City.

Raymond "Red" Reddington, one of the FBI's most wanted fugitives, surrenders in person at FBI Headquarters in Washington, D.C. He claims that he and the FBI have the same interests: bringing down dangerous criminals and terrorists. In the last two decades, he's made a list of criminals and terrorists that matter the most but the FBI cannot find because it does not know they exist. Reddington calls this "The Blacklist". Reddington will co-operate, but insists that he will speak only to Elizabeth Keen, a rookie FBI profiler.

Uptight and straight-laced, FBI Special Agent Sarah Ashburn is a methodical investigator with a reputation for excellence--and hyper-arrogance. Shannon Mullins, one of Boston P.D.'s "finest," is foul-mouthed and has a very short fuse, and uses her gut instinct and street smarts to catch the most elusive criminals. Neither has ever had a partner, or a friend for that matter. When these two wildly incompatible law officers join forces to bring down a ruthless drug lord, they become the last thing anyone expected: buddies.

Jeremy Fink and his best friend Lizzy must search high and low throughout the streets of Manhattan for clues to unlock the mysterious box he received a month before his birthday.

A young drug dealer watches as his high-rolling life is dismantled in the wake of his cousin's murder, which sees his best friend arrested for the crime.