In the aftermath of Stonewall, a newly politicized Vito Russo found his voice as a gay activist and critic of LGBTQ+ representation in the media. He went on to write "The Celluloid Closet", the first book to critique Hollywood's portrayals of gays on screen. During the AIDS crisis in the 1980s, Vito became a passionate advocate for justice via the newly formed ACT UP, before his death in 1990.

Rise Up And Shout! tells the story of four generations of creative gay voices in Los Angeles who unite to create a theatrical showcase for gay youth on September 9, 2006. In the process, a unique community is created made up of young and old, black and white, shy and loud -- including an 83 year-old priest and an 18 year old former prostitute and poet.