When a virus leaks from a top-secret facility, turning all resident researchers into ravenous zombies and their lab animals into mutated hounds from hell, the government sends in an elite military task force to contain the outbreak.

The American successful architect Michael Lewis travels to London with his partner and friend, the builder Jake, to refurbish an old hotel. Michael is having successive nightmares, and once in London, he realizes that twenty-one spirits are trying to contact him to solve murders of a serial killer. Michael, with the support of Jake, Detective Pryce and the ghosts, try to avoid the ninth crime and find the serial-killer.