When five sorority girls inadvertently cause the murder of one of their sisters in a prank gone wrong, they agree to keep the matter to themselves and never speak of it again, so they can get on with their lives. This proves easier said than done, when after graduation a mysterious killer goes after the five of them and anyone who knows their secret.

Lifelong platonic friends Zack and Miri look to solve their respective cash-flow problems by making an adult film together. As the cameras roll, however, the duo begin to sense that they may have more feelings for each other than they previously thought.