Marty is a shipping clerk in the garment district and a wise guy trying to cut corners and get by on angles, and not very good at it. He meets Helen and decides to change his ways, but lack of patience in slow-progress jobs leads him to become involved with a neighborhood gang.

New York Assistant District Attorney Howard Malloy is working hard on investigation about a series of murders related to an extremist group.

The Naked City portrays the police investigation that follows the murder of a young model. A veteran cop is placed in charge of the case and he sets about, with the help of other beat cops and detectives, finding the girl's killer.