Based on the Reginald Berkeley stage play, this compelling historical drama offers a depiction of the life story of Florence Nightingale, the young 19th-century Englishwoman famously drawn to a career in nursing. Traveling to Turkey during the Crimean War, Florence gains a reputation for being devoted to the care of wounded soldiers and for pioneering higher standards for sanitary hospital conditions.

On New Years Eve, 1899, baronet's son Edward Courtney becomes engaged to Kate, his mother's maid, much to the scandal of London society. The film then follows their family through four generations, with separations, joys, tragedies, and service in the Boer War, WWI, and WWII.

The Wiggs family plan to celebrate Thanksgiving in their rundown shack with leftover stew, without Mr. Wiggs who wandered off long ago an has never been heard from. Do-gooder Miss Lucy brings them a real feast. Her boyfriend Bob arranges to take Wiggs' sick boy to a hospital. Their other boy makes some money peddling kindling and takes the family to a show. Mrs. Wiggs is called to the hopsital just in time to see her boy die. Her neighbor Miss Mazy wants to marry Mr. Stubbins who insists on tasting her cooking. Mrs. Wiggs sneaks her dishes past Stubbins who agrees to marriage. Mr. Wiggs appears suddenly, in tatters, with just the amount of money (twenty dollars) needed to save the family from foreclosure. Miss Lucy and Bob get married.

A dying man meets a stranger at a bar.