On its way back to Earth, the space shuttle Nautilus passes through a cloud of alien spores causing its sole occupant, astronaut Steve Thomas to transform into a blood-thirsty monster. The shuttle crashes into a swampy region of central Florida, creating a situation which threatens contagion and/or death to all who encounter the shuttle or its mutated pilot.

Twenty years ago a deadly accident forced Eddie Burber from his home. Since Eddie was younger he wanted to be part of the family business "The Burber Haunted House." A note is placed on the local Fraternity giving permission to use the old house as a fund-raiser. While the students prepare the house, they soon are hunted down and placed in the Haunted House for amusement. One thing is for sure. Nobody knows it really happening - People are dying, and people are laughing.

A detective and a psychic investigate a series of murders at a trailer park, and suspect that some of the residents are doing the killings--and they are vampires.