Unrepentant Tennessee moonshine runner Luke Doolin (Robert Mitchum) makes dangerous high-speed deliveries for his liquor-producing father, Vernon (Trevor Bardette), but won't let his younger brother Robin (James Mitchum) join the family business. Under pressure from both out-of-town gangster Kogan (Jacques Aubuchon), who wants a piece of the local action, and Treasury agent Barrett (Gene Barry), who wants to destroy the moonshine business, Luke fights for his fast-fading way of life.

Alvin York a hillbilly sharpshooter transforms himself from ruffian to religious pacifist. He is then called to serve his country and despite deep religious and moral objections to fighting becomes one of the most celebrated American heroes of WWI.

This labor advocacy film is about diseases plaguing miners in Kansas, Missouri and Oklahoma. Sponsored by the Tri-State Survey Committee, "Men and Dust" is a stylistically innovative documentary and a valuable ecological record of landscapes radically transformed by extractive industry.