Cuban Bandleader Ricky Ricardo would be happy if his wife Lucy would just be a housewife. Instead she tries constantly to perform at the Tropicana where he works, and make life comically frantic in the apartment building they share with landlords Fred and Ethel Mertz, who also happen to be their best friends.

Nora Shelley is a tax expert for the accounting company which is led by Paul Martin. She thinks she can find a suitable husband by inspecting their clients' tax documents. Martin finds out and tries to dissuade her from this approach, later enlisting the help of his friend Steve Adams, who tries to woo Shelley.

While on shore leave to celebrate his first anniversary, Lt. Peter Duluth (Warren Douglas) takes his wife, Iris (Audrey Long), to a Los Angeles hotel but is turned away. When mysterious Colette (Stephanie Bachelor) offers them her suite, the young couple becomes entangled in a murder plot. Aided by two PIs, Peter and Iris find two corpses and are desperate to locate Colette before she becomes the next victim, but the killers are one step ahead.

A member of a band practicing for an upcoming commercial finds out from his girlfriend that she got a job as nurse to a rich but eccentric old man, Mr. Lark. Believing that music can cure those with mental problems, he and his band accompanies the nurse to Lark's mansion in order to "cure" him.

Jimmy joins Cannonball on a visit to the widow Fennamore, Cannonball's old girlfriend, at Firehole. Engineer Colton is killed by henchman Smoky Morgan and Philip Judson hides the body. The engineer, at the request of the widow's niece, Martha, had come to inspect a polluted reservoir. Land Company head Turner and Judson contaminated the water to get the ranchers to vacate so they can grab the land. Judson hires Easy to pose as the engineer, and he reports the reservoir useless but Jimmy's test proves the waters are not deeply polluted. Judson kills Easy to keep him from talking, and casts the blame on Cannonball. But Jimmy has a trick up his sleeve, right after the next song.

Newlyweds Eddie (Joe DeRita) and Betty (Christine McIntyre) barely moved into their new house before Betty's mother (Esther Howard), aunt (Patsy Moran) and brother (Charles Williams) show up and give every indication of becoming permanent free-loading guests. Dick (William Newell) gives Eddie a plan that will cause his unwanted guests to vacate the premises, by having Dick and his wife, Ruby (Dorothy Granger), move in as Eddie's relatives, and even bigger pests, thereby causing Betty's relatives to move out. The plan works and Eddie and Betty are pleased until Dick announces that he and Ruby have intentions of staying on.

Rival reporters (George Brent, Joan Blondell) investigate a Hollywood star (Adele Jergens) and the box she receives with a dead man inside.

The police commissioner asks some local street kids to toughen up his ballet-loving son.

The East Side Kids are pursued by killers seeking a stolen necklace.

The gang is friend with a millionaire because they saved him from an agression. However, the gang is suspecting that the man's son was actually one of the agressors.

Ordered by a judge to get a job, Muggs McGinnis is hired by wealthy Mrs. Murray, who has a penchant for picking up trouble-prone servants. At an engagement party for Mrs. Murray's spoiled daughter Brenda, Muggs enlists his pals as extra help.

A city girl on a bus tour of the West encounters a handsome rodeo cowboy who helps her forget her city suitors.

Small-town soda-jerk Peggy Evans quits her dead-end job and moves to New York where she invents a new identity.

The East Side Kids find a young girl in the apartment of a man who has just been murdered. Believing her to be innocent, they hide her in their clubhouse while they try to find the real killer. The killer, however, used a baseball bat as his murder weapon, and the bat has the fingerprints of one of the gang on it.

Hollywood starlet foils an Axis plot to sabotage the L.A. infrastructure.

A group of academics have spent years shut up in a house working on the definitive encyclopedia. When one of them discovers that his entry on slang is hopelessly outdated, he ventures into the wide world to learn about the evolving language. Here he meets Sugarpuss O’Shea, a nightclub singer, who’s on top of all the slang—and, it just so happens, needs a place to stay.

Egbert Sousé becomes an unexpected hero when a bank robber falls over a bench he's occupying. Now considered brave, Egbert is given a job as a bank guard. Soon, he is approached by charlatan J. Frothingham Waterbury about buying shares in a mining company. Egbert persuades teller Og Oggilby to lend him bank money, to be returned when the scheme pays off. Unfortunately, bank inspector Snoopington then makes a surprise appearance.

The drought-plagued ranchers of Sundown have to market their cattle at a loss in order to meet mortgage payments held by banker Cylus Cuttler. Then, Sheriff Tex Rockett is forced to quarantine all the cattle on the local ranches because of a hoof-and-mouth disease outbreak. Steve Davis herds his cattle to the railhead anyway, and Tex is forced to arrest him. Urged on by the banker's son, Nick Cuttler, the angry ranchers storm the jail, but Steve's sister Bee persuades them to await the trial. Steve, with Nick's help, breaks jail and is told he must kill Tex to aid the ranchers. Meanwhile, government man Bret Stockton and Tex see Nick and his men treating cattle in an unusual way. Tex finally proves that the Cuttlers have been treating the cattle with acid to give a false impression of the hoof-and-mouth disease.

The dangerous Ceegareet gang has control of Boom Town. No miner with rich diggings is safe from this murderous gang. Tex Roberts and his pal Slim Hunkafeller strike a pay vein and find themselves marked as the gang's next victims.

Stan and Ollie work in a horn factory. Ollie starts having violent fits every time he hears a horn. His doctor prescribes a restful sea voyage. Mayhem ensues.

Tom Turner, a naturalist, comes to the "Topa Topa" district (named for the mountain), and falls in love with widow Margaret Weston...

Elsa Carlyle is impulsive and a gambler. Though loved by her husband Jeff, she's spoiled and selfish, concerned with social standing. Meanwhile, Jeff wants to stop spending while he completes business deals that could make them rich. One night, on a hunch, she bets and loses big at a casino, then she doubles her problems with more impulsive decisions. Hardy Livingston, a wealthy Casanova just back from the Orient, makes a play for her. Elsa dallies with Hardy, but soon, his insistence and her dire financial affairs seem destined to lead to adultery. Who's the cheat?