Three showgirls on their way to Las Vegas have car trouble and are stuck all night out in the desert. The next morning cheerful Andre offers them help in fixing their car. However, Andre is really a maniac with a lot of family problems; his mother ran out on him when he was a child so now he keeps kidnapped women chained up in his barn and trains them to perform circus tricks. Andre's father is still around of course, but because the old homestead is next to a nuclear test site he has been transformed into a raving homicidal mutant that Andre keeps locked up in a shed.

"The Meadows Foundation" is a research laboratory run by dedicated scientist Dr. Flanders and his shapely assistant Dr. Phyllis Alcott. The place was named after their leader, Dr. Meadows, "an underground practicing abortionist." The two doctors, dressed in lab coats and clutching clipboards, conduct experiments on "surrogates" - people whose libidos are damaged. Mainly, they hook up battery cables to naked, spread-eagled women.